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ICD-10 Coding for BRCA2 Positive(Z15.01, Z15.02)

Complete ICD-10-CM coding and documentation guide for BRCA2 Positive. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

BRCA2 MutationBRCA2 Genetic Susceptibility

Related ICD-10 Code Ranges

Complete code families applicable to BRCA2 Positive

Z15-Z15.09Primary Range

Genetic susceptibility to malignant neoplasm

This range includes codes for genetic susceptibility to cancer, specifically Z15.01 for BRCA2 related breast cancer risk.

Family history of primary malignant neoplasm

This range includes codes for family history of cancer, which can be used as ancillary codes to support BRCA2 documentation.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
Z15.01Genetic susceptibility to malignant neoplasm of breastUse when a patient has a confirmed BRCA2 mutation that increases breast cancer risk.
  • Confirmed BRCA2 mutation via genetic testing
  • Risk assessment using models like Tyrer-Cuzick
Z15.02Genetic susceptibility to malignant neoplasm of ovaryUse when a patient has a confirmed BRCA2 mutation that increases ovarian cancer risk.
  • Confirmed BRCA2 mutation via genetic testing
  • Risk assessment using models like Penn II

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for BRCA2 positive

Essential facts and insights about BRCA2 Positive

The ICD-10 code for BRCA2 positive related to breast cancer risk is Z15.01.

Primary ICD-10-CM Codes for brca2 positive

Genetic susceptibility to malignant neoplasm of breast
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed BRCA2 mutation with increased breast cancer risk

Applicable To

  • BRCA2 mutation with breast cancer risk

Excludes

  • Genetic susceptibility to malignant neoplasm of ovary (Z15.02)

Clinical Validation Requirements

  • Confirmed BRCA2 mutation via genetic testing
  • Risk assessment using models like Tyrer-Cuzick

Code-Specific Risks

  • Incorrectly using Z14.8 instead of Z15.01

Coding Notes

  • Ensure genetic testing results are documented to support the use of Z15.01.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Family history of malignant neoplasm of breast

Z80.3
Use when there is a family history of breast cancer to support BRCA2 testing.

Family history of malignant neoplasm of ovary

Z80.4
Use when there is a family history of ovarian cancer to support BRCA2 testing.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Genetic susceptibility to malignant neoplasm of ovary

Z15.02
Use Z15.02 when the primary concern is ovarian cancer risk due to BRCA2 mutation.

Genetic susceptibility to malignant neoplasm of breast

Z15.01
Use Z15.01 when the primary concern is breast cancer risk due to BRCA2 mutation.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting BRCA2 Positive to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code Z15.01.

Impact

Clinical: Incomplete risk assessment, Regulatory: Non-compliance with documentation standards, Financial: Potential claim denials

Mitigation Strategy

Always document family history when relevant, Use templates to ensure completeness

Impact

Reimbursement: Incorrect coding may lead to claim denials., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate patient records and data reporting.

Mitigation Strategy

Use Z15.01 specifically for BRCA2 mutations related to breast cancer risk.

Impact

Incomplete documentation of genetic testing results can lead to audit findings.

Mitigation Strategy

Ensure all genetic test results and risk assessments are fully documented.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for BRCA2 Positive, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for BRCA2 Positive

Use these documentation templates to ensure complete and accurate documentation for BRCA2 Positive. These templates include all required elements for proper coding and billing.

BRCA2 Positive with Family History

Specialty: Oncology

Required Elements

  • Genetic test results
  • Family history details
  • Risk assessment scores

Example Documentation

Patient has BRCA2 c.5946del (p.Ser1982fs) mutation confirmed via next-generation sequencing. Family history includes mother with breast cancer at age 42.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has BRCA mutation.
Good Documentation Example
BRCA2 c.5946del (p.Ser1982fs) identified via next-generation sequencing. Tyrer-Cuzick 10-year risk score: 8.2%.
Explanation
The good example provides specific mutation details and risk assessment, supporting medical necessity.

Need help with ICD-10 coding for BRCA2 Positive? Ask your questions below.

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