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ICD-10 Coding for Cardiac Amyloidosis(E85.4, I43)

Complete ICD-10-CM coding and documentation guide for Cardiac Amyloidosis. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Amyloid CardiomyopathyATTR-CMAL Amyloidosis with Cardiac Involvement

Related ICD-10 Code Ranges

Complete code families applicable to Cardiac Amyloidosis

E85.0-E85.9Primary Range

Amyloidosis

This range includes codes for different types of amyloidosis, with E85.4 being specific for organ-limited amyloidosis affecting the heart.

Cardiomyopathy in diseases classified elsewhere

Used to code cardiomyopathy due to amyloidosis, indicating the cardiac involvement.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E85.4Organ-limited amyloidosisUse when amyloidosis is confirmed to be organ-limited to the heart.
  • 99mTc-PYP scan showing Grade 2-3 uptake
  • Negative serum free light chain assay
I43Cardiomyopathy in diseases classified elsewhereUse in conjunction with E85.4 to specify cardiomyopathy due to amyloidosis.
  • Echocardiographic evidence of restrictive cardiomyopathy
  • CMR findings consistent with amyloidosis

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for cardiac amyloidosis

Essential facts and insights about Cardiac Amyloidosis

The ICD-10 code for cardiac amyloidosis is E85.4, used with I43 for cardiomyopathy.

Primary ICD-10-CM Codes for cardiac amyloidosis

Organ-limited amyloidosis
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed cardiac involvement with amyloidosis

documentation Criteria

  • Detailed imaging and lab results confirming amyloidosis type

Applicable To

  • Cardiac amyloidosis
  • Amyloid cardiomyopathy

Excludes

Clinical Validation Requirements

  • 99mTc-PYP scan showing Grade 2-3 uptake
  • Negative serum free light chain assay

Code-Specific Risks

  • Incorrect sequencing with I43
  • Lack of specificity in amyloidosis type

Coding Notes

  • Ensure documentation specifies the type of amyloidosis and its cardiac involvement.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Heart transplant status

Z94.1
Use when the patient has undergone a heart transplant due to amyloidosis.

Diastolic heart failure

I50.3-
Use when heart failure with preserved ejection fraction is present.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Non-neuropathic heredofamilial amyloidosis

E85.0
Use E85.0 for systemic involvement without cardiac specificity.

Cardiomyopathy, unspecified

I42.9
Use I42.9 when the specific cause of cardiomyopathy is not determined.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Cardiac Amyloidosis to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E85.4.

Impact

Clinical: May lead to inappropriate treatment., Regulatory: Non-compliance with documentation standards., Financial: Potential for denied claims.

Mitigation Strategy

Use specific imaging and lab results, Query for missing information

Impact

Reimbursement: Incorrect sequencing can lead to reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Impacts the accuracy of clinical data.

Mitigation Strategy

Always sequence E85.4 before I43 to indicate the primary condition.

Impact

Failure to sequence E85.4 before I43.

Mitigation Strategy

Implement coding audits to ensure correct sequencing.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Cardiac Amyloidosis, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Cardiac Amyloidosis

Use these documentation templates to ensure complete and accurate documentation for Cardiac Amyloidosis. These templates include all required elements for proper coding and billing.

Cardiac Amyloidosis with Heart Failure

Specialty: Cardiology

Required Elements

  • Type of amyloidosis
  • Imaging results
  • Functional impact

Example Documentation

Patient with confirmed ATTR-CM, NYHA Class III, on tafamidis.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has cardiac amyloidosis.
Good Documentation Example
Patient with ATTR-CM confirmed by Grade 2 PYP uptake, NYHA Class III symptoms.
Explanation
The good example provides specific imaging and symptom details.

Need help with ICD-10 coding for Cardiac Amyloidosis? Ask your questions below.

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