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ICD-10 Coding for Crigler-Najjar Syndrome and CNS Lymphoma(E80.5, C83.390)

Complete ICD-10-CM coding and documentation guide for Crigler-Najjar Syndrome and CNS Lymphoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Crigler-Najjar Type 1Crigler-Najjar Type 2Primary CNS Lymphoma

Related ICD-10 Code Ranges

Complete code families applicable to Crigler-Najjar Syndrome and CNS Lymphoma

E80-E89Primary Range

Metabolic disorders

Includes Crigler-Najjar Syndrome under E80.5.

C81-C96Primary Range

Malignant neoplasms of lymphoid, hematopoietic and related tissue

Includes CNS Lymphoma under C83.390.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E80.5Crigler-Najjar syndromeUse for confirmed cases of Crigler-Najjar syndrome with genetic validation.
  • Total bilirubin >20 mg/dL in neonates without hemolysis
  • Genetic testing showing UGT1A1 mutations
C83.390Primary central nervous system lymphoma, unspecifiedUse for confirmed primary CNS lymphoma with no systemic involvement.
  • Biopsy confirming CD20+ B-cells
  • MRI showing brain/spinal cord lesions

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for Crigler-Najjar syndrome

Essential facts and insights about Crigler-Najjar Syndrome and CNS Lymphoma

The ICD-10 code for Crigler-Najjar syndrome is E80.5, used for confirmed cases with genetic testing.

Primary ICD-10-CM Codes for crigler-najjar syndrome lymphoma

Crigler-Najjar syndrome
Billable Code

Decision Criteria

clinical Criteria

  • Presence of high bilirubin levels without hemolysis

Applicable To

  • Crigler-Najjar Type 1
  • Crigler-Najjar Type 2

Excludes

Clinical Validation Requirements

  • Total bilirubin >20 mg/dL in neonates without hemolysis
  • Genetic testing showing UGT1A1 mutations

Code-Specific Risks

  • Misdiagnosis due to lack of genetic testing

Coding Notes

  • Ensure genetic testing is documented to confirm diagnosis.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Family history of other specified conditions

Z84.89
Use when there is a family history of UGT1A1 mutations.

Diffuse large B-cell lymphoma in remission

C83.3A
Use to indicate remission status.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Gilbert syndrome

E80.4
Lower bilirubin levels and response to phenobarbital.

Malignant neoplasm of central nervous system, unspecified

C72.9
Use only when lymphoma is not confirmed.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Crigler-Najjar Syndrome and CNS Lymphoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E80.5.

Impact

Clinical: Misrepresentation of patient's condition, Regulatory: Non-compliance with ICD-10 coding guidelines, Financial: Potential claim denials or delays

Mitigation Strategy

Verify diagnosis with biopsy results, Ensure documentation specifies primary CNS involvement

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with coding standards., Data Quality: Inaccurate clinical data and statistics.

Mitigation Strategy

Verify diagnosis with genetic and biopsy tests.

Impact

Risk of coding CNS lymphoma as unspecified CNS neoplasm.

Mitigation Strategy

Ensure biopsy and imaging results are documented.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Crigler-Najjar Syndrome and CNS Lymphoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Crigler-Najjar Syndrome and CNS Lymphoma

Use these documentation templates to ensure complete and accurate documentation for Crigler-Najjar Syndrome and CNS Lymphoma. These templates include all required elements for proper coding and billing.

Crigler-Najjar Syndrome Diagnosis

Specialty: Hepatology

Required Elements

  • Bilirubin levels
  • Genetic test results
  • Phenobarbital response

Example Documentation

Neonate with persistent jaundice, total bilirubin 24.5 mg/dL, UGT1A1 mutations confirmed.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Hyperbilirubinemia of unknown origin
Good Documentation Example
Confirmed Crigler-Najjar syndrome with genetic testing showing UGT1A1 mutations.
Explanation
The good example specifies genetic confirmation, essential for accurate coding.

Need help with ICD-10 coding for Crigler-Najjar Syndrome and CNS Lymphoma? Ask your questions below.

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