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ICD-10 Coding for Elevated Prolactin(E22.1, D35.2)

Complete ICD-10-CM coding and documentation guide for Elevated Prolactin. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

HyperprolactinemiaProlactin Elevation

Related ICD-10 Code Ranges

Complete code families applicable to Elevated Prolactin

E22.0-E23.7Primary Range

Disorders of pituitary gland

This range includes conditions related to pituitary gland dysfunction, including hyperprolactinemia.

Benign neoplasm of pituitary gland

Used when a prolactinoma is the cause of elevated prolactin.

Adverse effect of antipsychotics

Relevant for cases where elevated prolactin is due to medication effects.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E22.1HyperprolactinemiaUse when elevated prolactin is confirmed without an identifiable cause.
  • Prolactin levels >700 mIU/L
  • Exclusion of known causes
D35.2Benign neoplasm of pituitary glandUse when a prolactinoma is confirmed as the cause of elevated prolactin.
  • MRI confirmation of pituitary adenoma

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for elevated prolactin

Essential facts and insights about Elevated Prolactin

The ICD-10 code for elevated prolactin is E22.1, used when no identifiable cause is found.

Primary ICD-10-CM Codes for elevated prolactin

Hyperprolactinemia
Billable Code

Decision Criteria

clinical Criteria

  • Prolactin levels >700 mIU/L with no identifiable cause

coding Criteria

  • Exclusion of prolactinoma or medication-induced causes

Applicable To

  • Idiopathic hyperprolactinemia

Excludes

Clinical Validation Requirements

  • Prolactin levels >700 mIU/L
  • Exclusion of known causes

Code-Specific Risks

  • Incorrect use without ruling out other causes

Coding Notes

  • Ensure to document the cause if known, and sequence appropriately.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Hypopituitarism

E23.0
Use when secondary hypogonadism is present.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Benign neoplasm of pituitary gland

D35.2
Use when MRI confirms a pituitary adenoma.

Hyperprolactinemia

E22.1
Use E22.1 when no adenoma is present.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Elevated Prolactin to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E22.1.

Impact

Clinical: Inaccurate treatment planning., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Thoroughly evaluate and document all potential causes.

Impact

Reimbursement: May lead to claim denials if incorrect coding is used., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Ensure all potential causes are evaluated and documented.

Impact

Failure to sequence etiology before manifestation.

Mitigation Strategy

Educate staff on proper sequencing rules.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Elevated Prolactin, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Elevated Prolactin

Use these documentation templates to ensure complete and accurate documentation for Elevated Prolactin. These templates include all required elements for proper coding and billing.

Hyperprolactinemia due to prolactinoma

Specialty: Endocrinology

Required Elements

  • Prolactin levels
  • MRI findings
  • Symptoms

Example Documentation

Assessment: Hyperprolactinemia secondary to pituitary adenoma. Plan: Initiate cabergoline.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Elevated prolactin noted.
Good Documentation Example
Prolactin 2,800 mIU/L, MRI shows 8mm pituitary adenoma.
Explanation
The good example provides specific lab values and imaging findings.

Need help with ICD-10 coding for Elevated Prolactin? Ask your questions below.

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