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ICD-10 Coding for Factor V Leiden Mutation(D68.51, D68.59)

Complete ICD-10-CM coding and documentation guide for Factor V Leiden Mutation. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Factor V Leiden DeficiencyLeiden Thrombophiliafactor 5 leidenapc resistance

Related ICD-10 Code Ranges

Complete code families applicable to Factor V Leiden Mutation

D68.5-D68.6Primary Range

Other Coagulation Defects

This range includes codes for primary thrombophilia, including Factor V Leiden mutation.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D68.51Primary thrombophilia due to Factor V Leiden mutationUse when genetic testing confirms Factor V Leiden mutation.
  • Genetic confirmation via PCR or DNA analysis
  • Activated protein C resistance test
D68.59Other primary thrombophiliaUse when thrombophilia is suspected but not confirmed as Factor V Leiden.
  • Clinical suspicion of thrombophilia without specific genetic confirmation.

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for Factor V Leiden mutation

Essential facts and insights about Factor V Leiden Mutation

The ICD-10 code for confirmed Factor V Leiden mutation is D68.51. Use D68.59 for suspected thrombophilia without genetic confirmation.

Primary ICD-10-CM Codes for factor vomiting leiden mutation

Primary thrombophilia due to Factor V Leiden mutation
Billable Code

Decision Criteria

clinical Criteria

  • Genetic test confirms Factor V Leiden mutation.

documentation Criteria

  • Documentation specifies heterozygous or homozygous mutation.

Applicable To

  • Heterozygous Factor V Leiden mutation
  • Homozygous Factor V Leiden mutation

Excludes

  • Acquired thrombophilia (D68.59)

Clinical Validation Requirements

  • Genetic confirmation via PCR or DNA analysis
  • Activated protein C resistance test

Code-Specific Risks

  • Incorrectly coding as D68.59 without genetic confirmation.

Coding Notes

  • Ensure documentation specifies genetic confirmation of Factor V Leiden mutation.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Long-term (current) use of anticoagulants

Z79.01
Use when patient is on anticoagulation therapy.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Other primary thrombophilia

D68.59
Use when thrombophilia is suspected but not confirmed as Factor V Leiden.

Primary thrombophilia due to Factor V Leiden mutation

D68.51
Use when genetic testing confirms Factor V Leiden mutation.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Factor V Leiden Mutation to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D68.51.

Impact

Clinical: Potential mismanagement of patient care., Regulatory: Non-compliance with documentation standards., Financial: Incorrect billing and potential claim denials.

Mitigation Strategy

Ensure specific genetic test results are documented., Clarify any ambiguous terms with the provider.

Impact

Reimbursement: Incorrect coding may lead to improper DRG assignment., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate patient records and data reporting.

Mitigation Strategy

Verify genetic testing results and use D68.51 if confirmed.

Impact

Risk of audit if genetic confirmation is not documented for D68.51.

Mitigation Strategy

Ensure all genetic test results are included in the patient's record.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Factor V Leiden Mutation, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Factor V Leiden Mutation

Use these documentation templates to ensure complete and accurate documentation for Factor V Leiden Mutation. These templates include all required elements for proper coding and billing.

Confirmed Factor V Leiden mutation with DVT

Specialty: Hematology

Required Elements

  • Genetic test results
  • Current anticoagulation status
  • History of thrombotic events

Example Documentation

Patient with confirmed heterozygous Factor V Leiden mutation, currently on warfarin for recurrent DVT.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has thrombophilia.
Good Documentation Example
Patient with confirmed heterozygous Factor V Leiden mutation, on warfarin for recurrent DVT.
Explanation
The good example specifies the genetic confirmation and treatment details.

Need help with ICD-10 coding for Factor V Leiden Mutation? Ask your questions below.

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