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ICD-10 Coding for Factor V Leiden Thrombophilia(D68.59, D68.51)

Complete ICD-10-CM coding and documentation guide for Factor V Leiden Thrombophilia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Factor V Leiden MutationFVLActivated Protein C Resistance

Related ICD-10 Code Ranges

Complete code families applicable to Factor V Leiden Thrombophilia

D68.5-D68.6Primary Range

Other coagulation defects

This range includes codes for hereditary thrombophilia, including Factor V Leiden.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D68.59Other primary thrombophiliaUse when Factor V Leiden mutation is confirmed without specific mention of APC resistance.
  • Genetic testing confirming Factor V Leiden mutation
  • Personal or family history of venous thromboembolism
D68.51Activated protein C resistanceUse when documentation specifies resistance to activated protein C.
  • APC resistance assay showing reduced APC ratio
  • Genetic testing confirming Factor V Leiden mutation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for Factor V Leiden thrombophilia

Essential facts and insights about Factor V Leiden Thrombophilia

The ICD-10 code for Factor V Leiden thrombophilia is D68.59, used when the mutation is confirmed without specific mention of APC resistance.

Primary ICD-10-CM Codes for factor vomiting leiden thrombophilia

Other primary thrombophilia
Billable Code

Decision Criteria

clinical Criteria

  • Genetic testing confirms Factor V Leiden mutation

documentation Criteria

  • Documentation does not specify APC resistance

Applicable To

  • Hereditary thrombophilia
  • Factor V Leiden mutation

Excludes

  • Secondary thrombophilia (D68.69)

Clinical Validation Requirements

  • Genetic testing confirming Factor V Leiden mutation
  • Personal or family history of venous thromboembolism

Code-Specific Risks

  • Incorrectly using this code without genetic confirmation
  • Using as primary code when active clot is present

Coding Notes

  • Ensure genetic testing confirmation is documented.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Family history of thrombophilia

Z84.81
Use for patients with a family history of thrombophilia.

Long-term (current) use of anticoagulants

Z79.01
Use when the patient is on anticoagulant therapy.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Activated protein C resistance

D68.51
Use when documentation specifically mentions APC resistance.

Other primary thrombophilia

D68.59
Use when APC resistance is not specifically documented.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Factor V Leiden Thrombophilia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D68.59.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Specify type of thrombophilia in documentation, Include genetic test results

Impact

Reimbursement: Potential claim denial due to lack of supporting documentation., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate patient records and data.

Mitigation Strategy

Ensure genetic testing results are documented before coding.

Impact

Lack of genetic test documentation for D68.59.

Mitigation Strategy

Ensure all genetic tests are documented in the patient's record.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Factor V Leiden Thrombophilia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Factor V Leiden Thrombophilia

Use these documentation templates to ensure complete and accurate documentation for Factor V Leiden Thrombophilia. These templates include all required elements for proper coding and billing.

Hematology Clinic Visit

Specialty: Hematology

Required Elements

  • Genetic test results
  • Family history of thrombophilia
  • APC resistance assay results

Example Documentation

Patient presents with a confirmed heterozygous Factor V Leiden mutation. Genetic testing performed on [date]. Family history includes maternal DVT.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has thrombophilia.
Good Documentation Example
Patient has a confirmed heterozygous Factor V Leiden mutation, documented by genetic testing on [date].
Explanation
The good example provides specific genetic confirmation, which is necessary for accurate coding.

Need help with ICD-10 coding for Factor V Leiden Thrombophilia? Ask your questions below.

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