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ICD-10 Coding for Febrile Neutropenia(D70.9, D70.1, R50.81)

Complete ICD-10-CM coding and documentation guide for Febrile Neutropenia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Neutropenic FeverChemotherapy-induced Neutropenia with Fever

Related ICD-10 Code Ranges

Complete code families applicable to Febrile Neutropenia

D70-D77Primary Range

Other disorders of blood and blood-forming organs

Includes codes for neutropenia and related conditions.

General symptoms and signs

Includes codes for fever and other general symptoms.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D70.9Neutropenia, unspecifiedUse when neutropenia is present without a specified cause.
  • ANC <1,500/mm³ without documented cause
D70.1Agranulocytosis secondary to chemotherapyUse when neutropenia is directly linked to chemotherapy.
  • ANC <500/mm³ with recent chemotherapy
R50.81Fever presenting with conditions classified elsewhereUse when fever is present with neutropenia.
  • Temperature ≥38.3°C with ANC <1,000/mm³

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for febrile neutropenia

Essential facts and insights about Febrile Neutropenia

Febrile neutropenia is coded with D70.1 and R50.81.

Primary ICD-10-CM Codes for febrile neutropenia

Neutropenia, unspecified
Billable Code

Decision Criteria

clinical Criteria

  • ANC <1,500/mm³ without a specified cause

Applicable To

  • Unspecified neutropenia

Excludes

Clinical Validation Requirements

  • ANC <1,500/mm³ without documented cause

Code-Specific Risks

  • Risk of under-documenting the cause of neutropenia.

Coding Notes

  • Ensure documentation specifies if neutropenia is chemotherapy-induced.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Fever presenting with conditions classified elsewhere

R50.81
Use when fever is present with neutropenia.

Adverse effect of antineoplastic agents

T45.1X5
Use to indicate chemotherapy as the cause of neutropenia.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Agranulocytosis secondary to chemotherapy

D70.1
Use when neutropenia is due to chemotherapy.

Other pancytopenia

D61.818
Use when pancytopenia is present without specific neutropenia.

Fever, unspecified

R50.9
Use when fever is present without neutropenia.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Febrile Neutropenia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D70.9.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Non-compliance with documentation standards., Financial: Potential for denied claims.

Mitigation Strategy

Ensure cause of neutropenia is documented.

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate data on treatment outcomes.

Mitigation Strategy

Use D70.1 if neutropenia is due to chemotherapy.

Impact

Reimbursement: May affect DRG assignment and reimbursement., Compliance: Failure to comply with coding standards., Data Quality: Incomplete clinical data representation.

Mitigation Strategy

Use R50.81 to indicate fever with neutropenia.

Impact

Risk of coding neutropenia without specifying cause.

Mitigation Strategy

Ensure detailed documentation of chemotherapy and ANC.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Febrile Neutropenia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Febrile Neutropenia

Use these documentation templates to ensure complete and accurate documentation for Febrile Neutropenia. These templates include all required elements for proper coding and billing.

Febrile neutropenia in oncology

Specialty: Oncology

Required Elements

  • ANC values
  • Temperature readings
  • Chemotherapy details
  • Infection status

Example Documentation

Patient presents with ANC 300/mm³ and temp 38.9°C post-cycle 2 R-CHOP.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Low WBC and fever.
Good Documentation Example
ANC 400/mm³, temp 38.6°C, post-cycle DA-EPOCH-R.
Explanation
The good example provides specific ANC and temperature values and links to chemotherapy.

Need help with ICD-10 coding for Febrile Neutropenia? Ask your questions below.

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