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ICD-10 Coding for Gilbert's Disease(E80.4)

Complete ICD-10-CM coding and documentation guide for Gilbert's Disease. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Gilbert's SyndromeInherited Disorder of Bilirubin Metabolism

Related ICD-10 Code Ranges

Complete code families applicable to Gilbert's Disease

E80.0-E80.9Primary Range

Disorders of porphyrin and bilirubin metabolism

This range includes conditions related to bilirubin metabolism, including Gilbert syndrome.

Key Information: ICD-10 code for Gilbert's disease

Essential facts and insights about Gilbert's Disease

The ICD-10 code for Gilbert's disease is E80.4.

Primary ICD-10-CM Code for gilbert's disease

Gilbert syndrome
Billable Code

Decision Criteria

clinical Criteria

  • Unconjugated hyperbilirubinemia with normal liver function tests

documentation Criteria

  • Documented absence of hemolysis

Applicable To

  • Gilbert's syndrome
  • Inherited disorder of bilirubin metabolism

Excludes

  • Crigler-Najjar syndrome (E80.5)
  • Dubin-Johnson syndrome (E80.6)

Clinical Validation Requirements

  • Unconjugated hyperbilirubinemia <6 mg/dL
  • Normal liver function tests (ALT/AST <40 U/L)
  • Absence of hemolysis (normal CBC, LDH, haptoglobin)

Code-Specific Risks

  • Confusing with other hyperbilirubinemias
  • Not documenting absence of hemolysis

Coding Notes

  • Always sequence E80.4 first when Gilbert syndrome is the primary reason for the encounter.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Unspecified jaundice

R17
Use if jaundice is documented without specifying Gilbert syndrome.

Fatigue

R53.83
Use if fatigue is documented as a presenting symptom.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Crigler-Najjar syndrome

E80.5
Severe unconjugated hyperbilirubinemia (>20 mg/dL), UGT1A1 enzyme activity <10%

Dubin-Johnson syndrome

E80.6
Conjugated hyperbilirubinemia, dark liver pigment on biopsy

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Gilbert's Disease to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E80.4.

Impact

Clinical: May lead to misdiagnosis., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Always specify if bilirubin is unconjugated.

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Always code E80.4 first if confirmed.

Impact

Coding E80.4 without documented unconjugated hyperbilirubinemia.

Mitigation Strategy

Ensure all lab results are documented and meet criteria.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Gilbert's Disease, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Gilbert's Disease

Use these documentation templates to ensure complete and accurate documentation for Gilbert's Disease. These templates include all required elements for proper coding and billing.

Emergency Department Note

Specialty: Emergency Medicine

Required Elements

  • Patient history
  • Physical exam findings
  • Laboratory results
  • Diagnosis

Example Documentation

25yo male presents with scleral icterus after 24-hour fast. Total bilirubin 3.5 mg/dL (unconjugated 3.2 mg/dL), ALT 30 U/L, AST 32 U/L, LDH 150 U/L (ref: 100-190), haptoglobin 45 mg/dL (ref: 30-200). No hepatosplenomegaly. Diagnosis: Gilbert syndrome exacerbation.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Jaundice noted.
Good Documentation Example
Intermittent jaundice triggered by fasting; total bilirubin 2.8 mg/dL (unconjugated 2.5 mg/dL), ALT 25 U/L, AST 28 U/L, no hemolysis.
Explanation
The good example provides specific lab values and excludes other conditions.

Need help with ICD-10 coding for Gilbert's Disease? Ask your questions below.

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