ICD-10 Coding for Hyperparathyroidism(E21.0, E21.1, N25.81)
Complete ICD-10-CM coding and documentation guide for Hyperparathyroidism. Includes clinical validation requirements, documentation requirements, and coding pitfalls.
Also known as:
Related ICD-10 Code Ranges
Complete code families applicable to Hyperparathyroidism
E21.0-E21.3Primary Range
Hyperparathyroidism codes
This range covers all types of hyperparathyroidism, including primary, secondary, tertiary, and unspecified.
Secondary hyperparathyroidism of renal origin
Specifically used for secondary hyperparathyroidism due to chronic kidney disease.
Code Comparison: When to Use Each Code
Compare key differences between these codes to ensure accurate selection
| Code | Description | When to Use | Key Documentation |
|---|---|---|---|
| E21.0 | Primary hyperparathyroidism | Use when hyperparathyroidism is due to an overactive parathyroid gland, confirmed by lab and imaging results. |
|
| E21.1 | Secondary hyperparathyroidism, not elsewhere classified | Use when hyperparathyroidism is secondary to conditions like vitamin D deficiency. |
|
| N25.81 | Secondary hyperparathyroidism of renal origin | Use when hyperparathyroidism is secondary to chronic kidney disease. |
|
Clinical Decision Support
Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.
Key Information: ICD-10 code for primary hyperparathyroidism
Essential facts and insights about Hyperparathyroidism
Primary ICD-10-CM Codes for hyperparathyroid
Decision Criteria
clinical Criteria
- Presence of parathyroid adenoma on imaging
Applicable To
- Parathyroid adenoma
- Parathyroid hyperplasia
Excludes
- Secondary hyperparathyroidism (E21.1)
Clinical Validation Requirements
- Elevated serum calcium (>10.5 mg/dL)
- Elevated PTH (>65 pg/mL)
- Imaging confirming parathyroid adenoma
Code-Specific Risks
- Misclassification if secondary causes are not ruled out
Coding Notes
- Ensure documentation specifies primary hyperparathyroidism with supporting lab and imaging results.
E21.1 - Secondary hyperparathyroidism, not elsewhere classified
Use when hyperparathyroidism is secondary to conditions like vitamin D deficiency.
Applicable To
- Hyperparathyroidism due to vitamin D deficiency
Excludes
- Secondary hyperparathyroidism of renal origin (N25.81)
Clinical Validation Requirements
- Low 25-OH vitamin D (<20 ng/mL)
- Elevated PTH levels
Coding Notes
Document the underlying cause of secondary hyperparathyroidism.
N25.81 - Secondary hyperparathyroidism of renal origin
Use when hyperparathyroidism is secondary to chronic kidney disease.
Applicable To
- Hyperparathyroidism due to chronic kidney disease
Clinical Validation Requirements
- Elevated PTH with normal/low calcium
- eGFR <30
Coding Notes
Link with CKD stage for accurate coding.
Ancillary Codes
Additional codes that should be used in conjunction with the main diagnosis codes when applicable.
Osteoporosis
M85.80Differential Codes
Alternative codes to consider when ruling out similar conditions to the primary diagnosis.
Documentation & Coding Risks
Avoid these common documentation and coding issues when documenting Hyperparathyroidism to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E21.0.
Impact
Clinical: Misleading treatment plans, Regulatory: Non-compliance with coding standards, Financial: Potential claim denials
Mitigation Strategy
Always document underlying conditions, Use specific codes for causes
Impact
Reimbursement: May lead to reduced reimbursement rates, Compliance: Increases risk of audit failures, Data Quality: Decreases accuracy of health records
Mitigation Strategy
Always use specific codes like E21.0 or E21.1 when documentation supports it.
Impact
Using unspecified codes when specific documentation is available
Mitigation Strategy
Train staff to use specific codes based on documentation
Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.
Frequently Asked Questions
Common questions about ICD-10 coding for Hyperparathyroidism, with expert answers to help guide accurate code selection and documentation.
Documentation Templates for Hyperparathyroidism
Use these documentation templates to ensure complete and accurate documentation for Hyperparathyroidism. These templates include all required elements for proper coding and billing.
Primary hyperparathyroidism diagnosis
Specialty: EndocrinologyRequired Elements
- PTH levels
- Calcium levels
- Imaging results
Example Documentation
Examples: Poor vs. Good Documentation
Poor Documentation Example
Good Documentation Example
Explanation
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