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ICD-10 Coding for Hypogammaglobulinemia(D80.0, D80.1, D80.7)

Complete ICD-10-CM coding and documentation guide for Hypogammaglobulinemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Immunoglobulin deficiencyLow immunoglobulin levelslow gamma globulin levels

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Related ICD-10 Code Ranges

Complete code families applicable to Hypogammaglobulinemia

D80.0-D80.9Primary Range

Immunodeficiency with predominantly antibody defects

This range includes various forms of hypogammaglobulinemia, distinguishing hereditary, nonfamilial, and transient types.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D80.0Hereditary hypogammaglobulinemiaUse when genetic testing confirms hereditary hypogammaglobulinemia.
  • Family history of immunodeficiency
  • Genetic testing confirming specific mutations
  • IgG levels < 200 mg/dL
  • + 1 more
D80.1Nonfamilial hypogammaglobulinemiaUse for acquired hypogammaglobulinemia without a family history.
  • IgG levels < 400 mg/dL
  • Recurrent infections
  • Normal B-cell count
D80.7Transient hypogammaglobulinemia of infancyUse for infants with temporary IgG deficiency resolving by age 3.
  • IgG levels < 300 mg/dL in infants
  • Normalization of IgG by age 3

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for hereditary hypogammaglobulinemia

Essential facts and insights about Hypogammaglobulinemia

The ICD-10 code for hereditary hypogammaglobulinemia is D80.0, used when genetic testing confirms a hereditary form.

Primary ICD-10-CM Codes for hypogammaglobulinemia

D80.0
Hereditary hypogammaglobulinemia
Billable Code

Decision Criteria

clinical Criteria

  • Presence of genetic mutation associated with hereditary hypogammaglobulinemia.

Applicable To

  • X-linked agammaglobulinemia
  • Autosomal recessive agammaglobulinemia

Excludes

  • Nonfamilial hypogammaglobulinemia (D80.1)

Clinical Validation Requirements

  • Family history of immunodeficiency
  • Genetic testing confirming specific mutations
  • IgG levels < 200 mg/dL
  • Absent B-cells

Code-Specific Risks

  • Misclassification without genetic confirmation

Coding Notes

  • Ensure genetic confirmation is documented.
View Full Code Details

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Pneumonia, unspecified organism

J18.9
Use to document infections related to hypogammaglobulinemia.

Acute sinusitis, unspecified

J01.90
Document sinusitis as a complication.

Encounter for routine child health examination without abnormal findings

Z00.129
Use for well-child visits in infants with transient hypogammaglobulinemia.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Nonfamilial hypogammaglobulinemia

D80.1
Lack of family history and normal B-cell count.

Hereditary hypogammaglobulinemia

D80.0
Confirmed genetic mutation and family history.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Hypogammaglobulinemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D80.0.

Impact

Clinical: May lead to misdiagnosis and inappropriate treatment., Regulatory: Non-compliance with coding standards., Financial: Potential for claim denials.

Mitigation Strategy

Ensure genetic testing is ordered and results are documented., Educate staff on documentation requirements.

Impact

Reimbursement: May lead to claim denials or reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of patient records.

Mitigation Strategy

Query provider for specific type of hypogammaglobulinemia.

Impact

Inadequate documentation of IgG levels can lead to audit issues.

Mitigation Strategy

Implement regular audits of patient records to ensure compliance.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Hypogammaglobulinemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Hypogammaglobulinemia

Use these documentation templates to ensure complete and accurate documentation for Hypogammaglobulinemia. These templates include all required elements for proper coding and billing.

Hereditary Hypogammaglobulinemia

Specialty: Immunology

Required Elements

  • Family history
  • Genetic testing results
  • IgG levels
  • B-cell count

Example Documentation

Patient presents with recurrent infections. Family history reveals similar cases. Genetic testing confirms BTK mutation. IgG levels consistently < 200 mg/dL.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has low immunoglobulins.
Good Documentation Example
Patient has IgG 180 mg/dL, confirmed BTK mutation, and recurrent infections.
Explanation
The good example provides specific lab values and genetic confirmation, essential for accurate coding.

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