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ICD-10 Coding for Leukemia(C91.10, C92.02)

Complete ICD-10-CM coding and documentation guide for Leukemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Blood CancerLeukemic Disorder

Related ICD-10 Code Ranges

Complete code families applicable to Leukemia

C91-C95Primary Range

Leukemia

This range includes all types of leukemia, categorized by specific types and statuses such as acute, chronic, lymphocytic, and myeloid.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C91.10Chronic lymphocytic leukemia of B-cell type not having achieved remissionUse when CLL-B-cell type is confirmed and not in remission.
  • Lymphocytosis ≥5×10⁹/L
  • CD5+/CD23+ markers
C92.02Acute myeloid leukemia, in relapseUse when AML is confirmed to be in relapse.
  • Bone marrow biopsy confirming ≥20% blasts
  • Presence of FLT3-ITD or NPM1 mutation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for leukemia

Essential facts and insights about Leukemia

The ICD-10 code for leukemia depends on the type and status, such as C91.10 for CLL not in remission.

Primary ICD-10-CM Codes for leukemia

Chronic lymphocytic leukemia of B-cell type not having achieved remission
Billable Code

Decision Criteria

clinical Criteria

  • Presence of lymphocytosis and specific markers

Applicable To

  • CLL-B-cell type not in remission

Excludes

  • Acute lymphoblastic leukemia

Clinical Validation Requirements

  • Lymphocytosis ≥5×10⁹/L
  • CD5+/CD23+ markers

Code-Specific Risks

  • Misclassification if remission status is not documented

Coding Notes

  • Ensure documentation specifies B-cell type and remission status.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Enlarged lymph nodes

R59.9
Use when lymphadenopathy is present alongside CLL.

Thrombocytopenia

D59.1
Use when thrombocytopenia is present with AML.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Diffuse large B-cell lymphoma

C83.39
Confirmed by biopsy and absence of CLL markers

Acute myeloid leukemia, not having achieved remission

C92.00
Use when AML is not in remission and not in relapse.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Leukemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C91.10.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Non-compliance with documentation standards., Financial: Potential for denied claims due to insufficient documentation.

Mitigation Strategy

Ensure all genetic test results are included in the patient's record.

Impact

Reimbursement: May lead to reduced reimbursement if history codes are used incorrectly., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate representation of patient's current health status.

Mitigation Strategy

Ensure current status is documented and use active codes like C91.10 or C92.02.

Impact

Coding remission status without proper documentation.

Mitigation Strategy

Require bone marrow biopsy results to confirm remission status.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Leukemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Leukemia

Use these documentation templates to ensure complete and accurate documentation for Leukemia. These templates include all required elements for proper coding and billing.

Acute Myeloid Leukemia in Relapse

Specialty: Oncology

Required Elements

  • Diagnosis
  • Bone marrow biopsy results
  • Genetic markers
  • Treatment plan

Example Documentation

Diagnosis: AML in relapse. Bone marrow: 35% blasts, FLT3-ITD+. Treatment: Venetoclax initiated.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Leukemia, stable.
Good Documentation Example
Acute myeloid leukemia with NPM1 mutation, in relapse post-venetoclax. Bone marrow blasts 35%.
Explanation
The good example provides specific leukemia type, genetic markers, and current status.

Need help with ICD-10 coding for Leukemia? Ask your questions below.

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