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ICD-10 Coding for Liver Cancer(C22.0, C78.7, T86.49)

Complete ICD-10-CM coding and documentation guide for Liver Cancer. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Hepatic CancerHepatocellular CarcinomaLiver Cell Carcinomaprimary liver neoplasmintrahepatic cholangiocarcinoma

Related ICD-10 Code Ranges

Complete code families applicable to Liver Cancer

C22-C22.9Primary Range

Malignant neoplasms of liver and intrahepatic bile ducts

This range includes primary liver cancers such as hepatocellular carcinoma and other specified liver cancers.

Secondary malignant neoplasm of liver and intrahepatic bile duct

Used for coding metastatic liver cancer when the liver is a secondary site.

Complications of transplanted liver

Used when liver cancer is a complication of a liver transplant.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C22.0Liver cell carcinomaUse when hepatocellular carcinoma is confirmed as the primary liver cancer.
  • Biopsy confirmation
  • Elevated AFP levels
  • Imaging showing arterial hyperenhancement
C78.7Secondary malignant neoplasm of liverUse when liver cancer is secondary to another primary cancer.
  • Imaging confirming liver lesions
  • Identification of primary cancer site
T86.49Complications of transplanted liverUse when liver cancer is a complication of a liver transplant.
  • Documented transplant history
  • Imaging or biopsy showing complications

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for liver cancer

Essential facts and insights about Liver Cancer

The ICD-10 code for primary liver cancer, specifically hepatocellular carcinoma, is C22.0. For secondary liver cancer, use C78.7.

Primary ICD-10-CM Codes for liver cancer

Liver cell carcinoma
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed hepatocellular carcinoma via biopsy and imaging.

coding Criteria

  • Sequence after transplant complication codes if applicable.

Applicable To

  • Hepatocellular carcinoma

Excludes

  • Secondary liver cancer (C78.7)

Clinical Validation Requirements

  • Biopsy confirmation
  • Elevated AFP levels
  • Imaging showing arterial hyperenhancement

Code-Specific Risks

  • Misclassification if not confirmed by biopsy
  • Incorrect sequencing with transplant complications

Coding Notes

  • Ensure biopsy confirmation and specify if primary or secondary.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Unspecified cirrhosis of liver

K74.60
Use when cirrhosis is present alongside liver cancer.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Intrahepatic bile duct carcinoma

C22.1
Distinguished by location and histological findings specific to bile duct origin.

Liver cell carcinoma

C22.0
Primary liver cancer confirmed by biopsy.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Liver Cancer to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C22.0.

Impact

Clinical: Leads to potential misdiagnosis and inappropriate treatment., Regulatory: Non-compliance with coding standards., Financial: Claims may be denied due to lack of confirmation.

Mitigation Strategy

Ensure biopsy results are included in the patient's record., Verify documentation before coding.

Impact

Reimbursement: Incorrect coding can lead to denied claims or incorrect DRG assignment., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data affecting patient records.

Mitigation Strategy

Ensure documentation specifies whether liver cancer is primary or metastatic.

Impact

Reimbursement: Incorrect DRG assignment affecting reimbursement., Compliance: Non-compliance with sequencing rules., Data Quality: Misleading clinical data in patient records.

Mitigation Strategy

Always sequence transplant complication codes before malignancy codes.

Impact

Incorrect sequencing of transplant complications and cancer codes.

Mitigation Strategy

Regular training on sequencing rules and audit of coding practices.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Liver Cancer, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Liver Cancer

Use these documentation templates to ensure complete and accurate documentation for Liver Cancer. These templates include all required elements for proper coding and billing.

Hepatocellular carcinoma with cirrhosis

Specialty: Hepatology

Required Elements

  • Biopsy results
  • AFP levels
  • Imaging findings
  • Etiology (e.g., hepatitis, alcohol use)

Example Documentation

Patient diagnosed with hepatocellular carcinoma (C22.0) confirmed by biopsy. Underlying cirrhosis (K74.60) due to hepatitis C (B18.2). AFP elevated at 500 ng/mL. Treatment plan includes sorafenib.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Liver cancer, treatment ongoing.
Good Documentation Example
Hepatocellular carcinoma (C22.0) confirmed by biopsy, with cirrhosis (K74.60) due to hepatitis C (B18.2). AFP: 500 ng/mL. Treatment: sorafenib.
Explanation
The good example provides specific codes, confirms diagnosis with biopsy, and includes treatment details.

Need help with ICD-10 coding for Liver Cancer? Ask your questions below.

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