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ICD-10 Coding for Low White Blood Cells(D70.1, D72.818)

Complete ICD-10-CM coding and documentation guide for Low White Blood Cells. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

LeukopeniaLow WBCNeutropenia

Related ICD-10 Code Ranges

Complete code families applicable to Low White Blood Cells

D70-D77Primary Range

Other disorders of blood and blood-forming organs

This range includes codes for leukopenia and related conditions affecting white blood cell counts.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D70.1Agranulocytosis secondary to infectionUse when leukopenia is directly caused by an infectious process.
  • WBC <4,000/μL
  • Presence of infection confirmed by culture
D72.818Other specified disorders of white blood cellsUse when leukopenia is due to a specific drug or toxin.
  • WBC decline ≥30% from baseline post-drug initiation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for low white blood cells

Essential facts and insights about Low White Blood Cells

The ICD-10 code for low white blood cells varies by cause: D70.1 for infection-induced and D72.818 for drug-induced leukopenia.

Primary ICD-10-CM Codes for low white blood cells

Agranulocytosis secondary to infection
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed infection with leukopenia

Applicable To

  • Neutropenia due to infection

Excludes

  • Congenital neutropenia (D70.0)

Clinical Validation Requirements

  • WBC <4,000/μL
  • Presence of infection confirmed by culture

Code-Specific Risks

  • Misidentifying the cause of leukopenia can lead to incorrect coding.

Coding Notes

  • Ensure documentation specifies the infectious cause of leukopenia.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Fever, unspecified

R50.9
Use to document associated symptoms like fever.

Adverse effect of antineoplastic and immunosuppressive drugs

T45.1X5A
Use to document adverse drug reactions causing leukopenia.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Leukopenia, unspecified

D72.819
Use D72.819 when the cause of leukopenia is not specified or known.

Agranulocytosis secondary to infection

D70.1
Use D70.1 when leukopenia is due to infection, not drugs.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Low White Blood Cells to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D70.1.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Non-compliance with documentation standards., Financial: Potential for claim denials.

Mitigation Strategy

Use specific terms and include lab results, Link leukopenia to underlying cause

Impact

Reimbursement: May lead to denied claims or reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of clinical data.

Mitigation Strategy

Always use the most specific code available based on documentation.

Impact

Using unspecified codes when specific causes are documented.

Mitigation Strategy

Train staff on importance of documenting specific causes.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Low White Blood Cells, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Low White Blood Cells

Use these documentation templates to ensure complete and accurate documentation for Low White Blood Cells. These templates include all required elements for proper coding and billing.

Chemotherapy-induced leukopenia

Specialty: Oncology

Required Elements

  • Patient history
  • Chemotherapy regimen
  • WBC count
  • Symptoms of infection

Example Documentation

Patient presents with leukopenia (WBC 3,200/μL) secondary to chemotherapy. No signs of infection. Plan: G-CSF ordered.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has low WBC.
Good Documentation Example
Patient presents with leukopenia (WBC 3,200/μL) secondary to chemotherapy, confirmed by CBC.
Explanation
The good example provides specific lab values and links the condition to chemotherapy.

Need help with ICD-10 coding for Low White Blood Cells? Ask your questions below.

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