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ICD-10 Coding for Neuroblastoma(C47.0, C49.9, C79.51)

Complete ICD-10-CM coding and documentation guide for Neuroblastoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Adrenal neuroblastomaPeripheral neuroblastoma

Related ICD-10 Code Ranges

Complete code families applicable to Neuroblastoma

C47-C49Primary Range

Malignant neoplasms of peripheral nerves and autonomic nervous system

This range includes codes for neuroblastoma based on the primary site of the tumor.

Secondary malignant neoplasm of other sites

This range is used for coding metastatic sites of neuroblastoma.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C47.0Malignant neoplasm of peripheral nerves of head, face and neckUse when neuroblastoma is confirmed in the adrenal gland.
  • Histopathological confirmation of neuroblastoma
  • MYCN amplification status
  • INRG stage documentation
C49.9Malignant neoplasm of connective and soft tissue, unspecifiedUse for neuroblastoma in peripheral nerves or autonomic nervous system.
  • Imaging confirmation of neuroblastoma in non-adrenal sites
  • Biopsy results
C79.51Secondary malignant neoplasm of boneUse when neuroblastoma has metastasized to the bone.
  • mIBG scan confirmation of bone metastases

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for neuroblastoma

Essential facts and insights about Neuroblastoma

The ICD-10 code for neuroblastoma is C47.0 for adrenal sites and C49.9 for peripheral sites.

Primary ICD-10-CM Codes for neuroblastoma

Malignant neoplasm of peripheral nerves of head, face and neck
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed diagnosis of neuroblastoma in the adrenal gland

Applicable To

  • Adrenal neuroblastoma

Excludes

  • Benign neoplasm of peripheral nerves (D36.1)

Clinical Validation Requirements

  • Histopathological confirmation of neuroblastoma
  • MYCN amplification status
  • INRG stage documentation

Code-Specific Risks

  • Misclassification if primary site is not specified

Coding Notes

  • Ensure documentation specifies the primary site and laterality.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Encounter for antineoplastic chemotherapy

Z51.11
Use when the encounter is primarily for chemotherapy administration.

Encounter for antineoplastic immunotherapy

Z51.12
Use when the encounter is primarily for immunotherapy administration.

Bone marrow transplant status

Z94.81
Use when patient has undergone a bone marrow transplant.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Benign neoplasm of peripheral nerves

D36.1
Histopathology confirming benign nature

Benign neoplasm of connective and soft tissue, unspecified

D21.9
Benign histological findings

Malignant neoplasm of bone and articular cartilage, unspecified

C41.9
Primary bone tumor histology

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Neuroblastoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C47.0.

Impact

Clinical: Inaccurate risk assessment and treatment planning, Regulatory: Non-compliance with oncology documentation standards, Financial: Potential reimbursement issues due to incomplete documentation

Mitigation Strategy

Standardize inclusion of MYCN status in all neuroblastoma reports, Regular audits of oncology documentation

Impact

Reimbursement: Potential claim denial due to lack of specificity, Compliance: Non-compliance with ICD-10 coding guidelines, Data Quality: Inaccurate clinical data affecting treatment decisions

Mitigation Strategy

Ensure documentation includes laterality of the adrenal gland.

Impact

Reimbursement: Incorrect DRG assignment leading to financial loss, Compliance: Violation of coding sequencing rules, Data Quality: Misleading data on treatment encounters

Mitigation Strategy

Sequence Z51.11 before the primary neuroblastoma code.

Impact

Failure to document complete INRG staging can lead to audit issues.

Mitigation Strategy

Implement mandatory staging documentation in EHR templates.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Neuroblastoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Neuroblastoma

Use these documentation templates to ensure complete and accurate documentation for Neuroblastoma. These templates include all required elements for proper coding and billing.

Neuroblastoma with chemotherapy

Specialty: Oncology

Required Elements

  • Primary site and laterality
  • INRG stage
  • MYCN status
  • Current treatment regimen

Example Documentation

Patient with stage M neuroblastoma of the left adrenal gland (C47.0), MYCN amplified, currently on cycle 2 of chemotherapy (Z51.11).

Examples: Poor vs. Good Documentation

Poor Documentation Example
Neuroblastoma, continue chemo.
Good Documentation Example
Stage M neuroblastoma of left adrenal gland (C47.0), MYCN amplified, cycle 2 of chemotherapy (Z51.11).
Explanation
The good example provides specific details on the stage, site, and treatment, ensuring accurate coding and billing.

Need help with ICD-10 coding for Neuroblastoma? Ask your questions below.

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