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ICD-10 Coding for Neutropenia(D70.0, D70.1, D70.3)

Complete ICD-10-CM coding and documentation guide for Neutropenia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Low Neutrophil CountAgranulocytosis

Related ICD-10 Code Ranges

Complete code families applicable to Neutropenia

D70.0-D70.9Primary Range

Neutropenia and related conditions

This range includes all forms of neutropenia, specifying different causes and severities.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D70.0AgranulocytosisUse when agranulocytosis is confirmed by lab tests and clinical evaluation.
  • ANC <500/μL
  • Bone marrow biopsy showing agranulocytosis
D70.1Agranulocytosis secondary to chemotherapyUse when neutropenia is a direct result of chemotherapy treatment.
  • ANC <500/μL post-chemotherapy
  • Documented chemotherapy regimen
D70.3Neutropenia due to infectionUse when neutropenia is caused by an infectious process.
  • ANC <500/μL with positive infection culture

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for chemotherapy-induced neutropenia

Essential facts and insights about Neutropenia

The ICD-10 code for chemotherapy-induced neutropenia is D70.1, used with Z51.11 for chemotherapy encounters.

Primary ICD-10-CM Codes for neutropenia

Agranulocytosis
Billable Code

Decision Criteria

clinical Criteria

  • ANC <500/μL confirmed by CBC

documentation Criteria

  • Bone marrow biopsy results included

Applicable To

  • Agranulocytosis due to drugs
  • Agranulocytosis due to infection

Excludes

  • Neutropenia due to chemotherapy (D70.1)

Clinical Validation Requirements

  • ANC <500/μL
  • Bone marrow biopsy showing agranulocytosis

Code-Specific Risks

  • Misclassification if not confirmed by lab results

Coding Notes

  • Ensure documentation specifies agranulocytosis and any underlying causes.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Encounter for antineoplastic chemotherapy

Z51.11
Use with D70.1 to indicate chemotherapy-related neutropenia.

Sepsis, unspecified organism

A41.9
Use to specify the infectious cause of neutropenia.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Agranulocytosis secondary to chemotherapy

D70.1
Use D70.1 if neutropenia is directly linked to chemotherapy treatment.

Agranulocytosis

D70.0
Use D70.0 if neutropenia is not related to chemotherapy.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Neutropenia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D70.0.

Impact

Clinical: Misleading clinical picture, Regulatory: Non-compliance with coding standards, Financial: Potential loss of reimbursement

Mitigation Strategy

Ensure chemotherapy details are included in patient records, Regular audits of oncology documentation

Impact

Reimbursement: May lead to lower reimbursement rates., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of health data.

Mitigation Strategy

Ensure documentation supports the most specific code available.

Impact

High risk of audit if unspecified codes are used without justification.

Mitigation Strategy

Ensure all documentation supports the most specific code available.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Neutropenia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Neutropenia

Use these documentation templates to ensure complete and accurate documentation for Neutropenia. These templates include all required elements for proper coding and billing.

Chemotherapy patient with neutropenia

Specialty: Oncology

Required Elements

  • ANC levels
  • Chemotherapy regimen
  • Infection signs

Example Documentation

**Subjective**: "Fatigue, fever 100.8°F x 24h" **Objective**: - ANC: 320/μL (↓ from 1,200 1 week prior) - CXR: No infiltrates - Blood cultures: Pending **Assessment**: 1. Febrile neutropenia (D70.1) secondary to cycle 2 AC chemo (Z51.11) 2. Rule out sepsis (A41.9) **Plan**: - Start cefepime per neutropenic fever protocol - Hold chemo until ANC >1,500

Examples: Poor vs. Good Documentation

Poor Documentation Example
"Neutropenia noted"
Good Documentation Example
"ANC 380/μL, no recent chemotherapy; etiology under investigation via bone marrow biopsy"
Explanation
The good example provides specific ANC levels and investigation details, supporting accurate coding.

Need help with ICD-10 coding for Neutropenia? Ask your questions below.

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