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ICD-10 Coding for Neutropenic Fever(D70.1, D70.9, R50.81)

Complete ICD-10-CM coding and documentation guide for Neutropenic Fever. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Febrile NeutropeniaNeutropenia with Fever

Related ICD-10 Code Ranges

Complete code families applicable to Neutropenic Fever

D70-D77Primary Range

Diseases of the blood and blood-forming organs

This range includes codes for neutropenia and related conditions.

General symptoms and signs

This range includes codes for fever and other general symptoms.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D70.1Agranulocytosis secondary to antineoplastic chemotherapyUse when neutropenia is due to chemotherapy and accompanied by fever.
  • ANC <500/mm³
  • Temperature ≥38.3°C
  • Chemotherapy history
D70.9Neutropenia, unspecifiedUse when the cause of neutropenia is not specified.
  • ANC <500/mm³
  • Fever ≥38.3°C
R50.81Fever presenting with conditions classified elsewhereUse when fever is present with neutropenia.
  • Temperature ≥38.3°C

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for neutropenic fever

Essential facts and insights about Neutropenic Fever

The ICD-10 code for neutropenic fever secondary to chemotherapy is D70.1. For unspecified neutropenia with fever, use D70.9.

Primary ICD-10-CM Codes for neutropenic fever

Agranulocytosis secondary to antineoplastic chemotherapy
Billable Code

Decision Criteria

clinical Criteria

  • ANC <500/mm³ and fever present

documentation Criteria

  • Chemotherapy documented as cause

Applicable To

  • Chemotherapy-induced neutropenia with fever

Excludes

Clinical Validation Requirements

  • ANC <500/mm³
  • Temperature ≥38.3°C
  • Chemotherapy history

Code-Specific Risks

  • Incorrectly coding without chemotherapy documentation

Coding Notes

  • Ensure chemotherapy is documented as the cause of neutropenia.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Adverse effect of antineoplastic drugs

T45.1X5A
Use with D70.1 to indicate chemotherapy as the cause.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Neutropenia, unspecified

D70.9
Use when the cause of neutropenia is not specified.

Agranulocytosis secondary to antineoplastic chemotherapy

D70.1
Use when chemotherapy is the documented cause.

Drug-induced fever

R50.2
Use when fever is explicitly documented as drug-induced.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Neutropenic Fever to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D70.1.

Impact

Clinical: Inaccurate diagnosis of neutropenic fever., Regulatory: Non-compliance with ICD-10 documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Use EHR templates with required fields, Regular training on documentation standards

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Only code R50.2 if explicitly documented as drug-induced.

Impact

Reimbursement: Claims may be rejected due to Excludes1 note., Compliance: Violation of ICD-10 coding rules., Data Quality: Misrepresentation of patient condition.

Mitigation Strategy

Use D70.1 with D64.81 and D69.59 instead.

Impact

Lack of chemotherapy documentation can lead to audit issues.

Mitigation Strategy

Implement mandatory documentation fields in EHR.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Neutropenic Fever, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Neutropenic Fever

Use these documentation templates to ensure complete and accurate documentation for Neutropenic Fever. These templates include all required elements for proper coding and billing.

Febrile neutropenia post-chemotherapy

Specialty: Oncology

Required Elements

  • ANC levels
  • Temperature readings
  • Chemotherapy details

Example Documentation

Patient presents with ANC 450/mm³ and temperature 39.1°C post FOLFOX chemotherapy.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Neutropenic fever
Good Documentation Example
Febrile neutropenia (ANC 300/mm³) secondary to cycle 2 of paclitaxel
Explanation
The good example specifies ANC, temperature, and chemotherapy details.

Need help with ICD-10 coding for Neutropenic Fever? Ask your questions below.

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