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ICD-10 Coding for Polycythemia Vera(D45)

Complete ICD-10-CM coding and documentation guide for Polycythemia Vera. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Primary PolycythemiaVaquez Diseasevaquez's diseasepvpolycythemia rubra veraprv

Related ICD-10 Code Ranges

Complete code families applicable to Polycythemia Vera

D45Primary Range

Polycythemia vera

This is the primary code for diagnosing polycythemia vera, a myeloproliferative disorder characterized by increased red blood cell mass.

Other and unspecified diseases of blood and blood-forming organs

Includes secondary polycythemia, which must be differentiated from polycythemia vera.

Key Information: ICD-10 code for polycythemia vera

Essential facts and insights about Polycythemia Vera

The ICD-10 code for polycythemia vera is D45, used for diagnosing this myeloproliferative disorder.

Primary ICD-10-CM Code for polycythemia vera

Polycythemia vera
Billable Code

Decision Criteria

clinical Criteria

  • Presence of JAK2 mutation and low serum EPO

documentation Criteria

  • Detailed lab results and bone marrow biopsy findings

Applicable To

  • Primary polycythemia
  • Vaquez disease

Excludes

  • Secondary polycythemia (D75.1)

Clinical Validation Requirements

  • Hgb >16.5 g/dL in men or >16.0 g/dL in women
  • HCT >49% in men or >48% in women
  • JAK2 V617F mutation positive
  • Subnormal serum erythropoietin level

Code-Specific Risks

  • Incorrectly coding secondary polycythemia as D45
  • Missing documentation of JAK2 mutation

Coding Notes

  • Ensure documentation includes all WHO criteria for diagnosis.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

JAK2 exon 12 sequencing

81403
Use for genetic testing to confirm JAK2 mutations.

JAK2 V617F variant analysis

81404
Use for genetic testing to confirm JAK2 mutations.

Long-term use of hydroxyurea

Z79.891
Use when documenting long-term medication management for polycythemia vera.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Secondary polycythemia

D75.1
Characterized by elevated EPO levels and absence of JAK2 mutation.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Polycythemia Vera to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D45.

Impact

Clinical: May lead to misdiagnosis., Regulatory: Non-compliance with diagnostic criteria., Financial: Potential claim denials due to incomplete documentation.

Mitigation Strategy

Ensure genetic testing is completed and documented., Review lab results before finalizing diagnosis.

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with ICD-10 coding guidelines., Data Quality: Inaccurate clinical data affecting patient records.

Mitigation Strategy

Use D75.1 for secondary causes of polycythemia.

Impact

Failure to document JAK2 mutation can lead to audit issues.

Mitigation Strategy

Ensure all genetic test results are included in patient records.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Polycythemia Vera, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Polycythemia Vera

Use these documentation templates to ensure complete and accurate documentation for Polycythemia Vera. These templates include all required elements for proper coding and billing.

Initial Diagnosis of Polycythemia Vera

Specialty: Hematology

Required Elements

  • Hgb and HCT levels
  • JAK2 mutation status
  • Serum EPO level
  • Bone marrow biopsy results

Example Documentation

Patient presents with Hgb 18.0 g/dL, HCT 52%, JAK2 V617F positive. Bone marrow biopsy shows trilineage hyperplasia.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Elevated RBC count noted.
Good Documentation Example
Hgb 17.2 g/dL, HCT 51%, JAK2 V617F positive, serum EPO 1.8 mU/mL.
Explanation
The good example provides specific lab values and mutation status, meeting WHO criteria.

Need help with ICD-10 coding for Polycythemia Vera? Ask your questions below.

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